Vasopressin

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Dose:   0.3 milliunits to 2 milliunits/kg/min

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Frequency:  Continuous infusion
 

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Comments: Treatment of refractory hypotension due to vasodilitation (as would be seen with sepsis). Dose estimation based on  case report of 11 infants and children following cardiac surgery. Not recommended by the American Heart Association due to insufficient evidence.
 

bulletToxicity: Hypertension, arrhythmias, bradycardia, cardiac arrest, bronchoconstriction, tremor, urticaria. Skin necrosis associated with extravasation due to IV infiltrate.
 
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Preparation: Vasopressin will be prepared in the pharmacy in a 0.2 units/ml concentration to be used with a programable infusion pump. When ordering the drug, write for a "continuous vasopressin infusion, 0.2 unit/ml concentration at x milliunits/kg/min."  The infusion rate programed from the pump can be double checked after 8/12 using the drip sheet calculator (must have microsoft excel installed).  Discard after 24 hours. 

 

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Compatibility:


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